Sisters

George Clooney (45): Clooney has had rabid fans since his supporting role on "Sisters," but "ER" shot him into heartthrob territory, where he's been resting comfortably ever since. Resolutely single, he nonetheless radiates sex appeal in every role, from "Ocean's Thirteen" to ... moremore offbeat or serious parts in films such as "Syriana" and "Good Night, and Good Luck," which he also directed. There've been whispers about a run for office, but we don't really care, as long as we get to gaze on that statesmanlike face. (Armando Gallo/Retna Ltd.)