5. "X-Men: The Last Stand"
Releasing: May 26
Estimated Take: $220 million
Why: It's being billed as the "final" chapter of a series no one knew was a trilogy (did you?). It's the only major movie opening on Memorial Day weekend. It will face competition from "Poseidon," "Da Vinci" and "Hedge," but being the new kid on the holiday is huge. Plus, it faces no real threats in its genre until "Superman Returns" opens five weeks later.
What To Look For: Lots and lots of death. Unless, of course, the studio changes its mind at the last minute and wants the whole gang to come back for "X4."

4. "Click"
Releasing: June 23
Estimated Take: $230 million
Why: Last summer Adam Sandler starred in the abominable "The Longest Yard" and managed to wring $160 million out of it. This summer he's starring in a comedy that actually looks funny and should appeal to teens, adults and kids. Lesson learned? Never doubt Happy Gilmore's appeal, especially in a PG-13 movie.
What To Look For: Kate Beckinsale as a housewife. You'd buy it, right?

3. "Superman Returns"
Releasing: June 30
Estimated Take: $275 million
Why: It's been almost 20 years since a "Superman" movie was released, and this one aims to return the franchise to greatness. So why won't it be number one? It's most likely going to end up over two-and-a-half hours long, and there is that little "Pirates" movie opening only one week later.
What To Look For: Lex Luthor still loves real estate, except this time he won't settle for just sinking California into the ocean.

2. "Over The Hedge"
Releasing: May 19
Estimated Take: $325 million
Why: This is a tough one. Word is "Hedge" is much better than last summer's uneven "Madagascar." However, four weeks after "Hedge" opens it faces what will definitely be a monster opening for Pixar's "Cars." Will "Hedge" appeal enough to adults and kids to let it weather the storm? The Hitlist says yes.
What To Look For: Steve Carell stealing the show (again) as Hammy the crazy, rabid squirrel.

1. "Pirates of the Caribbean: Dead Man's Chest"
Releasing: July 7
Estimated Take: $325 million
Why: There is a treasure trove of reasons. After "Superman," it's the last big blockbuster to hit theaters, and that gives it very little competition in the family-film market. Also, there is that little thing of audiences loving Johnny Depp as Captain Jack Sparrow.
What To Look For: More supernatural craziness and a special surprise that leads into the third "Pirates" movie.

Potential Breakouts: Jack Black is "Nacho Libre"; the already cult-worthy "Snakes on a Plane"; Jennifer and Vince in "The Break Up"; the Sundance lovefest "Little Miss Sunshine"; Justin Long makes up college in "Accepted"; and Uma flies in "My Super Ex-Girlfriend."